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Omegaven and Other Alternative Lipids for Treating Liver Disease

Hau D. Le, MD (2010)

Children’s Hospital, Boston, MA
Parenteral Fish Oil-Based Lipid Emulsion Improved Lipid and Fatty Acid
Profiles in Parenteral Nutrition-Dependent Patients (Abstract, DVD)

Ordering Information (2016)
Update on Omegaven (2007)
Discovering a new Treatment (2006)
What’s Up with Omegaven (Update 7/09) Power Point Presentation

 

Other recent research in this area:

Elimination of soybean lipid emulsion in parenteral nutrition and supplementation with enteral fish oil improve cholestasis in infants with short bowel syndrome [a retrospective review of four infants who received EN fish oil] Rollins MD, Scaife ER, Jackson WD, Meyers RL, Mulroy CW, Book LS.
Source Children’s Medical Center, University of Utah, Salt Lake City, Utah 84113-1103 Nutr Clin Pract. 2010 Apr;25(2):199-204.
(Abstract, Article)

 

Fish oil containing intravenous lipid emulsions in parenteral nutrition-associated cholestatic liver disease [a summary of current data, published in 2010] Koletzko B, Goulet O. SourceDivision of Metabolic and Nutritional Medicine, Dr von Hauner Children’s Hospital, University of Munich Medical Center, Munich, Germany. Curr Opin Clin Nutr Metab Care. 2010 May;13(3):321-6 (Abstract)

 

Author’s Summary: The observed improvement of PNAC on parenteral lipids with fish oil deserves further exploration. No controlled trials are available, nutritional adequacy and safety of 100% fish oil emulsions are not adequately documented, and currently their use cannot be considered standard care. First data on mixed lipid emulsions with some fish oil are encouraging, and their effects in PNAC should also be explored.

Review and Clinical Update on Parenteral Nutrition–Associated Liver Disease [This article reviews recent literature relating to the pathophysiology and treatment of PNALD] Emma M. Tillman, PharmD University of Tennessee Health Science Center, Memphis, Tennessee (Article)


Updated March 29, 2016

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9/26/2016 » 9/30/2016
Malnutrition Awareness Week

5/6/2017
Oley Regional Conference

This website is an educational resource. It is not intended to provide medical advice or recommend a course of treatment. You should discuss all issues, ideas, suggestions, etc. with your clinician prior to use. Clinicians in a relevant field have reviewed the medical information; however, the Oley Foundation does not guarantee the accuracy of the information presented, and is not liable if information is incorrect or incomplete. If you have questions please contact Oley staff.

 

Updated in 2015 with a generous grant from Shire, Inc. 

 

This website was updated in 2015 with a generous grant from Shire, Inc. This website is an educational resource. It is not intended to provide medical advice or recommend a course of treatment. You should discuss all issues, ideas, suggestions, etc. with your clinician prior to use. Clinicians in a relevant field have reviewed the medical information; however, the Oley Foundation does not guarantee the accuracy of the information presented, and is not liable if information is incorrect or incomplete. If you have questions please contact Oley staff.
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